Difference between revisions of "Dimethylformamide"

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A clear, toxic liquid that is considered a universal [[solvent]] since it is miscible in both water and organic solvents. Dimethylformamide (DMF) dissolves most natural and synthetic resins, and, with heat and time, DMF will even soften [[epoxy]]. It is often used in liquid chromatographic systems as a gradient intermediate between polar and nonpolar solvents. DMF is also used in some commercial paint stripping formulations.
 
A clear, toxic liquid that is considered a universal [[solvent]] since it is miscible in both water and organic solvents. Dimethylformamide (DMF) dissolves most natural and synthetic resins, and, with heat and time, DMF will even soften [[epoxy]]. It is often used in liquid chromatographic systems as a gradient intermediate between polar and nonpolar solvents. DMF is also used in some commercial paint stripping formulations.
 
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[[[SliderGallery rightalign|dimethylformamide.jpg~Chemical structure]]]
 
== Synonyms and Related Terms ==
 
== Synonyms and Related Terms ==
  
 
DMF; DMFA; n,n-dimethyl formamide
 
DMF; DMFA; n,n-dimethyl formamide
  
[[[SliderGallery rightalign|dimethylformamide.jpg~Chemical structure]]]
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== Risks ==
 +
 
 +
* Carcinogenic. 
 +
* Overexposure may cause vomiting, liver damage and high blood pressure. 
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* Irritant to skin. 
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* Combustible; moderate fire risk.  Flash point = 58C 
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* Toxic by inhalation, ingestion and skin absorption. 
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* Greenfield: [https://greenfield.com/wp-content/uploads/2018/11/DIMETHYLFORMAMIDE-DMF-SDS_US-English.pdf SDS]
  
== Other Properties ==
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==Physical and Chemical Properties==
  
 
Miscible with water and most common organic solvents.
 
Miscible with water and most common organic solvents.
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|-
 
|-
 
! scope="row"| Melting Point
 
! scope="row"| Melting Point
| -61
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| -61 C
 
|-
 
|-
 
! scope="row"| Density
 
! scope="row"| Density
| 0.9445
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| 0.9445 g/ml
 
|-
 
|-
 
! scope="row"| Molecular Weight
 
! scope="row"| Molecular Weight
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|-
 
|-
 
! scope="row"| Boiling Point
 
! scope="row"| Boiling Point
| 153
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| 153 C
 
|}
 
|}
 
== Hazards and Safety ==
 
 
Carcinogenic.  Overexposure may cause vomiting, liver damage and high blood pressure.  Irritant to skin.  Combustible; moderate fire risk.  Flash point = 58C 
 
 
Toxic by inhalation, ingestion and skin absorption. 
 
 
LINK: [http://www.cdc.gov/niosh/ipcsneng/neng0457.html International Chemical Safety Card]
 
  
 
== Comparisons ==
 
== Comparisons ==
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[[media:download_file_125.pdf|Properties of Common Solvents]]
 
[[media:download_file_125.pdf|Properties of Common Solvents]]
  
 
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==Resources and Citations==
 
 
== Authority ==
 
  
 
* ''The Merck Index'', Martha Windholz (ed.), Merck Research Labs, Rahway NJ, 10th edition, 1983  Comment: entry 9232
 
* ''The Merck Index'', Martha Windholz (ed.), Merck Research Labs, Rahway NJ, 10th edition, 1983  Comment: entry 9232

Latest revision as of 14:05, 21 July 2022

Description

A clear, toxic liquid that is considered a universal Solvent since it is miscible in both water and organic solvents. Dimethylformamide (DMF) dissolves most natural and synthetic resins, and, with heat and time, DMF will even soften Epoxy. It is often used in liquid chromatographic systems as a gradient intermediate between polar and nonpolar solvents. DMF is also used in some commercial paint stripping formulations.

Chemical structure

Dimethylformamide.jpg

Synonyms and Related Terms

DMF; DMFA; n,n-dimethyl formamide

Risks

  • Carcinogenic.
  • Overexposure may cause vomiting, liver damage and high blood pressure.
  • Irritant to skin.
  • Combustible; moderate fire risk. Flash point = 58C
  • Toxic by inhalation, ingestion and skin absorption.
  • Greenfield: SDS

Physical and Chemical Properties

Miscible with water and most common organic solvents.

Composition HCON(CH3)2
CAS 68-12-2
Melting Point -61 C
Density 0.9445 g/ml
Molecular Weight mol. wt. = 73.09
Boiling Point 153 C

Comparisons

Properties of Common Solvents

Resources and Citations

  • The Merck Index, Martha Windholz (ed.), Merck Research Labs, Rahway NJ, 10th edition, 1983 Comment: entry 9232
  • Hermann Kuhn, Conservation and Restoration of Works of Art and Antiquities, Butterworths, London, 1986