Morpholino ethanesulfonic acid

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Odorless, white crystalline material. Morpholino ethanesulfonic acid, or MES, is used as a buffering agent commonly used in biology and biochemistry. The mid-range buffer is water soluble, is stable in most chemicals and enzymes, and does not complex with metal ions. MES has minimal absorption in the UV/Vis spectral range.

Synonyms and Related Terms

morpholino (ethane sulfonic acid); MES; 2-(N-morpholino) ethanesulfonic acid; 4-morpholineethansulfonic acid monohydrate;

Chemical structure

Morpholino ethanesulfonic acid.jpg

Other Properties

Soluble in water. pKa = 6.15

Composition C6H13NO4S . H20
CAS 4432-31-9
Melting Point ~300 C
Molecular Weight mol. wt. = 213.25

Hazards and Safety

Contact may cause irritation.

Mallinckrodt Baker: MSDS


  • Richard C. Wolbers, Nanette T. Sterman, Chris Stavroudis, Richard C. Wolbers, Nanette T. Sterman, Chris Stavroudis, Notes for Workshop on New Methods in the Cleaning of Paintings, J.Paul Getty Trust, Los Angeles, 1990

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