Difference between revisions of "Methylene blue"

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== Description ==
 
== Description ==
  
Dark green crystals that form a deep blue aqueous solution. Methylene blue was first prepared in 1876 by Caro. It is a synthetic [http://cameo.mfa.org/materials/fullrecord.asp?name=aniline%20dye aniline dye] that was used a lightfast colorant for [http://cameo.mfa.org/materials/fullrecord.asp?name=cotton cotton], [http://cameo.mfa.org/materials/fullrecord.asp?name=silk silk], and [http://cameo.mfa.org/materials/fullrecord.asp?name=wool wool] (often with zinc as a mordant). Methylene blue is used as a biological stain for bacteria and as an indicator in oxidation-reduction reactions. Methylene blue is also used as a [http://cameo.mfa.org/materials/fullrecord.asp?name=disinfectant disinfectant] and an antidote for [http://cameo.mfa.org/materials/fullrecord.asp?name=sodium%20cyanide cyanide] poisoning.
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Dark green crystals that form a deep blue aqueous solution. Methylene blue was first prepared in 1876 by Caro. It is a synthetic  
 
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[[aniline%20dye|aniline dye]] that was used a lightfast colorant for  
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[[cotton|cotton]],  
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[[silk|silk]], and  
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[[wool|wool]] (often with zinc as a mordant). Methylene blue is used as a biological stain for bacteria and as an indicator in oxidation-reduction reactions. Methylene blue is also used as a  
 +
[[disinfectant|disinfectant]] and an antidote for  
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[[sodium%20cyanide|cyanide]] poisoning.
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[[[SliderGallery rightalign|methylene blue.jpg~Chemical structure]]]
 
== Synonyms and Related Terms ==
 
== Synonyms and Related Terms ==
  
 
methylthionine chloride; Basic Blue 9; CI 52015; Solvent Blue 8; 3,7-bis(dimethylamino)phenothiazin-5-ium chloride; azul de metileno (Esp.); azul de metileno (Port.); methyl blue; solvent blue; Basic Lake Blue; Swiss blue
 
methylthionine chloride; Basic Blue 9; CI 52015; Solvent Blue 8; 3,7-bis(dimethylamino)phenothiazin-5-ium chloride; azul de metileno (Esp.); azul de metileno (Port.); methyl blue; solvent blue; Basic Lake Blue; Swiss blue
  
[[[SliderGallery rightalign|methylene blue.jpg~Chemical structure]]]
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==Risks ==
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* Toxic by ingestion and inhalation. 
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* Contact may cause irritation. 
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* Potential teratogen. 
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* Flammable.  Flash point = 178 C 
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* Fisher Scientific: [https://fscimage.fishersci.com/msds/96419.htm MSDS]
  
== Other Properties ==
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==Physical and Chemical Properties==
  
 
Soluble in water, ethanol, chloroform.  pH of aq. solution = 3 - 4.5   
 
Soluble in water, ethanol, chloroform.  pH of aq. solution = 3 - 4.5   
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|-
 
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! scope="row"| Melting Point
 
! scope="row"| Melting Point
| 190 (dec)
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| 190 C (dec)
 
|-
 
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! scope="row"| Molecular Weight
 
! scope="row"| Molecular Weight
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== Hazards and Safety ==
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==Resources and Citations==
 
 
Toxic by ingestion and inhalation.  Contact may cause irritation. 
 
 
 
Potential teratogen. 
 
 
 
Flammable.  Flash point = 178 C. 
 
 
 
Fisher Scientific: [https://fscimage.fishersci.com/msds/96419.htm MSDS]
 
 
 
== Sources Checked for Data in Record ==
 
  
 
* Richard S. Lewis, ''Hawley's Condensed Chemical Dictionary'', Van Nostrand Reinhold, New York, 10th ed., 1993
 
* Richard S. Lewis, ''Hawley's Condensed Chemical Dictionary'', Van Nostrand Reinhold, New York, 10th ed., 1993

Latest revision as of 14:41, 1 October 2022

Description

Dark green crystals that form a deep blue aqueous solution. Methylene blue was first prepared in 1876 by Caro. It is a synthetic Aniline dye that was used a lightfast colorant for Cotton, Silk, and Wool (often with zinc as a mordant). Methylene blue is used as a biological stain for bacteria and as an indicator in oxidation-reduction reactions. Methylene blue is also used as a Disinfectant and an antidote for cyanide poisoning.

Chemical structure

Methylene blue.jpg

Synonyms and Related Terms

methylthionine chloride; Basic Blue 9; CI 52015; Solvent Blue 8; 3,7-bis(dimethylamino)phenothiazin-5-ium chloride; azul de metileno (Esp.); azul de metileno (Port.); methyl blue; solvent blue; Basic Lake Blue; Swiss blue

Risks

  • Toxic by ingestion and inhalation.
  • Contact may cause irritation.
  • Potential teratogen.
  • Flammable. Flash point = 178 C
  • Fisher Scientific: MSDS

Physical and Chemical Properties

Soluble in water, ethanol, chloroform. pH of aq. solution = 3 - 4.5

Insoluble in ether.

Composition C16H18N3SCl-3H2O
CAS 61-73-4
Melting Point 190 C (dec)
Molecular Weight mol. wt. = 319.85

Resources and Citations

  • Richard S. Lewis, Hawley's Condensed Chemical Dictionary, Van Nostrand Reinhold, New York, 10th ed., 1993
  • Random House, Webster's Encyclopedic Unabridged Dictionary of the English Language, Grammercy Book, New York, 1997
  • The Merck Index, Martha Windholz (ed.), Merck Research Labs, Rahway NJ, 10th edition, 1983 Comment: entry 6137
  • The American Heritage Dictionary or Encarta, via Microsoft Bookshelf 98, Microsoft Corp., 1998
  • A.Scharff, 'Synthetic dyestuffs for textiles and their fastness to washing', ICOM-CC Preprints Lyon, Getty Conservation Institute, Los Angeles, 1999
  • Colour Index International online at www.colour-index.org

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