Acetanilide

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Acetanilide

Description

A white, odorless powder that has a burning taste. Acetanilide is produced from aniline using Acetic acid. The shiny, leaflet crystals are stable in air. Acetanilide was used in the 19th century to treat fever and headaches but was discontinued because of toxic side effects. It is still used in the manufacture of medicines and dyes, as an accelerator for rubber Vulcanization, as a stabilizer for Cellulose ester dopes and lacquers, and as a synthetic Camphor.

Synonyms and Related Terms

n-phenylacetamide; antifebrin; acetylaniline; acetylaminobenzene; acetic acid anilide; acetanil; n-acetylaniline; n-phenyl acetamide

Chemical structure

Acetanilide.jpg


Risks

  • Highly toxic by ingestion.
  • Causes cyanosis.
  • Skin contact and inhalation cause irritation.
  • Fisher Scientific: SDS

Physical and Chemical Properties

Soluble in hot water, ethanol, ether, chloroform, acetone, glycerol and benzene.

Composition C8H9NO
CAS 103-84-4
Melting Point 114-116 C
Density 1.2105 g/ml
Molecular Weight mol. wt.=135.17
Boiling Point 303.8 C

Resources and Citations

  • Richard S. Lewis, Hawley's Condensed Chemical Dictionary, Van Nostrand Reinhold, New York, 10th ed., 1993
  • The Merck Index, Martha Windholz (ed.), Merck Research Labs, Rahway NJ, 10th edition, 1983
  • The American Heritage Dictionary or Encarta, via Microsoft Bookshelf 98, Microsoft Corp., 1998