Difference between revisions of "Trichloroacetic acid"

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== Description ==
 
== Description ==
  
White, deliquescent crystals precipitate [http://cameo.mfa.org/materials/fullrecord.asp?name=protein proteins] and is used as a reagent for the detection of [http://cameo.mfa.org/materials/fullrecord.asp?name=albumin albumin]. Trichloroacetic acid is used in the manufacture of pharmaceuticals and herbicides.
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White, deliquescent crystals precipitate [[protein|proteins]] and is used as a reagent for the detection of [[albumin|albumin]]. Trichloroacetic acid is used in the manufacture of pharmaceuticals and herbicides.
 
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[[[SliderGallery rightalign|trichloroacetic acid.jpg~Chemical structure]]]
 
== Synonyms and Related Terms ==
 
== Synonyms and Related Terms ==
  
 
TCA
 
TCA
  
[[[SliderGallery rightalign|trichloroacetic acid.jpg~Chemical structure]]]
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== Risks ==
  
== Other Properties ==
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* Toxic by ingestion and inhalation.
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* Highly corrosive on contact.
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* Decomposes to form chloroform, hydrochloric acid, carbon dioxide, carbon monoxide. 
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* ThermoFisher: [https://www.fishersci.com/msdsproxy%3FproductName%3DBP5551%26productDescription%3DTRICHLOROACETIC%2BACID%2B1KG%26catNo%3DBP555-1%26vendorId%3DVN00033897%26storeId%3D10652 SDS]
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==Physical and Chemical Properties==
  
Soluble in water, ethanol, ether.  pH  = 1.2 (for 0.1 M solution).
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* Soluble in water, ethanol, ether.   
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* pH  = 1.2 (for 0.1 M solution).
  
 
{| class="wikitable"
 
{| class="wikitable"
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|-
 
|-
 
! scope="row"| Melting Point
 
! scope="row"| Melting Point
| 57-58
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| 57-58 C
 
|-
 
|-
 
! scope="row"| Density
 
! scope="row"| Density
| 1.6298
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| 1.6298 g/ml
 
|-
 
|-
 
! scope="row"| Molecular Weight
 
! scope="row"| Molecular Weight
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|-
 
|-
 
! scope="row"| Boiling Point
 
! scope="row"| Boiling Point
| 196-197
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| 196-197 C
 
|}
 
|}
  
== Hazards and Safety ==
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==Resources and Citations==
 
 
Toxic by ingestion and inhalation. Highly corrosive on contact. Decomposes to form chloroform, hydrochloric acid, carbon dioxide, carbon monoxide. 
 
 
 
Mallinckrodt Baker: [http://www.jtbaker.com/msds/englishhtml/t4823.htm MSDS]
 
 
 
== Sources Checked for Data in Record ==
 
  
 
* Richard S. Lewis, ''Hawley's Condensed Chemical Dictionary'', Van Nostrand Reinhold, New York, 10th ed., 1993
 
* Richard S. Lewis, ''Hawley's Condensed Chemical Dictionary'', Van Nostrand Reinhold, New York, 10th ed., 1993

Latest revision as of 11:52, 16 June 2022

Description

White, deliquescent crystals precipitate proteins and is used as a reagent for the detection of Albumin. Trichloroacetic acid is used in the manufacture of pharmaceuticals and herbicides.

Chemical structure

Trichloroacetic acid.jpg

Synonyms and Related Terms

TCA

Risks

  • Toxic by ingestion and inhalation.
  • Highly corrosive on contact.
  • Decomposes to form chloroform, hydrochloric acid, carbon dioxide, carbon monoxide.
  • ThermoFisher: SDS

Physical and Chemical Properties

  • Soluble in water, ethanol, ether.
  • pH = 1.2 (for 0.1 M solution).
Composition CCl3COOH
CAS 76-03-9
Melting Point 57-58 C
Density 1.6298 g/ml
Molecular Weight mol. wt. = 163.39
Boiling Point 196-197 C

Resources and Citations

  • Richard S. Lewis, Hawley's Condensed Chemical Dictionary, Van Nostrand Reinhold, New York, 10th ed., 1993
  • Random House, Webster's Encyclopedic Unabridged Dictionary of the English Language, Grammercy Book, New York, 1997
  • The Merck Index, Martha Windholz (ed.), Merck Research Labs, Rahway NJ, 10th edition, 1983 Comment: entry 9756