Tris(hydroxymethyl)aminomethane

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Description

White, crystalline solid. Tris(hydroxymethyl)aminomethane is used as an emulsifying agent for oils, fats and waxes. It is also mixed in equally proportions with its corresponding hydrochloric acid salt and used as a buffer (see Trizma).

Synonyms and Related Terms

tris; tris hydroxymethyl aminomethane; THAM; 2-amino-2-hydroxymethyl-1,3-propanediol; tris amine buffer

Chemical structure

Tris(hydroxymethyl)aminomethane.jpg


Other Properties

Soluble in water (pH = 10.36 for 0.1 M solution).

Composition (CH2OH)3CNH2
CAS 77-86-1
Melting Point 171-172
Molecular Weight mol. wt. = 121.14
Boiling Point 219-220

Hazards and Safety

Combustible. Corrosive to copper, brass, aluminum.

Harmful by ingestion and inhalation. Skin contact causes irritation and burns.

Mallinckrodt Baker: MSDS

Sources Checked for Data in Record

  • Richard S. Lewis, Hawley's Condensed Chemical Dictionary, Van Nostrand Reinhold, New York, 10th ed., 1993
  • Richard C. Wolbers, Nanette T. Sterman, Chris Stavroudis, Notes for Workshop on New Methods in the Cleaning of Paintings, J.Paul Getty Trust, Los Angeles, 1990

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