Hexachlorophene

Description

A topical disinfectant formerly used as a major component in disinfectant soaps, such as pHisohex. Hexachlorophene, first patented in 1941, was restricted for use in 1972.

Synonyms and Related Terms

2,2'-methylenebis[3,4,6-trichlorphenol]; AT-7; G-11; Bilevon; Dermadex; Exofene; Gamophen; Hexosan; pHisohex; Surgi-Cen; Surofene; Acigena; Almederm; AT17; Fostril; G-11; Germa-Medica; Septisol

Risks

• Excessive dosage causes neurotoxicity.
• Usage regulated in U.S. by FDA in 1972.
• Cayman Chemical: SDS

Physical and Chemical Properties

Soluble in alcohol, acetone, ether, chloroform, propylene glycol, olive oil, cottonseed oil, benzene. Insoluble in water.

Composition	C13H6Cl6O2
CAS	70-30-4
Melting Point	164-165 C
Molecular Weight	mol. wt. = 406.92

Resources and Citations

• Richard S. Lewis, Hawley's Condensed Chemical Dictionary, Van Nostrand Reinhold, New York, 10th ed., 1993

• Random House, Webster's Encyclopedic Unabridged Dictionary of the English Language, Grammercy Book, New York, 1997

• The Merck Index, Martha Windholz (ed.), Merck Research Labs, Rahway NJ, 10th edition, 1983 Comment: entry 4716