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A topical disinfectant formerly used as a major component in disinfectant soaps, such as pHisohex. Hexachlorophene, first patented in 1941, was restricted for use in 1972.

Synonyms and Related Terms

2,2'-methylenebis[3,4,6-trichlorphenol]; AT-7; G-11; Bilevon; Dermadex; Exofene; Gamophen; Hexosan; pHisohex; Surgi-Cen; Surofene; Acigena; Almederm; AT17; Fostril; G-11; Germa-Medica; Septisol


  • Excessive dosage causes neurotoxicity.
  • Usage regulated in U.S. by FDA in 1972.
  • Cayman Chemical: SDS

Physical and Chemical Properties

Soluble in alcohol, acetone, ether, chloroform, propylene glycol, olive oil, cottonseed oil, benzene. Insoluble in water.

Composition C13H6Cl6O2
CAS 70-30-4
Melting Point 164-165 C
Molecular Weight mol. wt. = 406.92

Resources and Citations

  • Richard S. Lewis, Hawley's Condensed Chemical Dictionary, Van Nostrand Reinhold, New York, 10th ed., 1993
  • Random House, Webster's Encyclopedic Unabridged Dictionary of the English Language, Grammercy Book, New York, 1997
  • The Merck Index, Martha Windholz (ed.), Merck Research Labs, Rahway NJ, 10th edition, 1983 Comment: entry 4716