Difference between revisions of "Tetrahydrofuran"

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== Description ==
 
== Description ==
  
Colorless, transparent liquid with an ether-like odor. Tetrahydrofuran (THF) is a strong solvent for natural and synthetic resins, especially [http://cameo.mfa.org/materials/fullrecord.asp?name=vinyl%20resin vinyls]. It is used in the manufacture of [http://cameo.mfa.org/materials/fullrecord.asp?name=coating coatings], [http://cameo.mfa.org/materials/fullrecord.asp?name=adhesive adhesives], [http://cameo.mfa.org/materials/fullrecord.asp?name=magnetic%20tape magnetic tapes], [http://cameo.mfa.org/materials/fullrecord.asp?name=printing%20ink printing inks], and [http://cameo.mfa.org/materials/fullrecord.asp?name=cellophane cellophane]. Because THF is soluble in both water and organic solvents, it is chosen as an intermediate carrier in liquid chromatography solvent cycles.
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Colorless, transparent liquid with an ether-like odor. Tetrahydrofuran (THF) is a strong solvent for natural and synthetic resins, especially [[vinyl%20resin|vinyls]]. It is used in the manufacture of [[coating|coatings]], [[adhesive|adhesives]], [[magnetic%20tape|magnetic tapes]], [[printing%20ink|printing inks]], and [[cellophane|cellophane]]. Because THF is soluble in both water and organic solvents, it is chosen as an intermediate carrier in liquid chromatography solvent cycles.
  
 
== Synonyms and Related Terms ==
 
== Synonyms and Related Terms ==
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[[[SliderGallery rightalign|tetrahydrofuran.jpg~Chemical structure]]]
 
[[[SliderGallery rightalign|tetrahydrofuran.jpg~Chemical structure]]]
  
== Other Properties ==
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== Risks ==
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* Flammable. Fire risk.
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* Toxic by ingestion and inhalation.
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* Skin contact may cause irritation.
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* ThermoFisher: [https://www.fishersci.com/store/msds?partNumber=BP11401&productDescription=TETRAHYDROFURAN+SEQ+1L&vendorId=VN00033897&countryCode=US&language=en SDS]
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* EPA lists tetrahydrofuran as hazardous waste (ignitable, toxic); Concentrations over 10% must be disposed of appropriately
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== Physical and Chemical Properties ==
  
 
Soluble in water and organic solvents.
 
Soluble in water and organic solvents.
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|-
 
|-
 
! scope="row"| Melting Point
 
! scope="row"| Melting Point
| -108.4
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| -108.4 C
 
|-
 
|-
 
! scope="row"| Density
 
! scope="row"| Density
| 0.888-0.889
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| 0.888-0.889 g/ml
 
|-
 
|-
 
! scope="row"| Molecular Weight
 
! scope="row"| Molecular Weight
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|-
 
|-
 
! scope="row"| Boiling Point
 
! scope="row"| Boiling Point
| 66
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| 66 C
 
|}
 
|}
 
== Hazards and Safety ==
 
 
Flammable.  Fire risk. Toxic by ingestion and inhalation. Skin contact may cause irritation.
 
 
LINK: [http://www.cdc.gov/niosh/ipcsneng/neng0578.html International Chemical Safety Card]
 
  
 
== Comparisons ==
 
== Comparisons ==
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[[media:download_file_137.pdf|Properties of Common Solvents]]
 
[[media:download_file_137.pdf|Properties of Common Solvents]]
  
 
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==Resources and Citations==
 
 
== Sources Checked for Data in Record ==
 
  
 
* ''The Merck Index'', Susan Budavari (ed.), Merck Research Labs, Whitehouse Station, NJ, 12th Edition, 1996  Comment: entry 9351
 
* ''The Merck Index'', Susan Budavari (ed.), Merck Research Labs, Whitehouse Station, NJ, 12th Edition, 1996  Comment: entry 9351

Latest revision as of 13:31, 17 April 2024

Description

Colorless, transparent liquid with an ether-like odor. Tetrahydrofuran (THF) is a strong solvent for natural and synthetic resins, especially vinyls. It is used in the manufacture of coatings, adhesives, magnetic tapes, printing inks, and Cellophane. Because THF is soluble in both water and organic solvents, it is chosen as an intermediate carrier in liquid chromatography solvent cycles.

Synonyms and Related Terms

THF; diethylene oxide; tetramethylene oxide; 1,4-epoxybutane; oxacyclopentane; Oxolane

Chemical structure

Tetrahydrofuran.jpg


Risks

  • Flammable. Fire risk.
  • Toxic by ingestion and inhalation.
  • Skin contact may cause irritation.
  • ThermoFisher: SDS
  • EPA lists tetrahydrofuran as hazardous waste (ignitable, toxic); Concentrations over 10% must be disposed of appropriately

Physical and Chemical Properties

Soluble in water and organic solvents.

Composition C4H8O
CAS 109-99-9
Melting Point -108.4 C
Density 0.888-0.889 g/ml
Molecular Weight mol. wt. = 72.11
Refractive Index 1.4070
Boiling Point 66 C

Comparisons

Properties of Common Solvents

Resources and Citations

  • The Merck Index, Susan Budavari (ed.), Merck Research Labs, Whitehouse Station, NJ, 12th Edition, 1996 Comment: entry 9351
  • G.G. Hawley, The Condensed Chemical Dictionary, Reinhold Publishing, New York, 6th ed., 1961
  • Van Nostrand's Scientific Encyclopedia, Douglas M. Considine (ed.), Van Nostrand Reinhold, New York, 1976

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