Dansyl chloride

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A Fluorescent dye primarily used to detect proteins. Dansyl chloride has yellow orange crystals. It is also used in fluorescent labeling and as a detection agent for column chromatography.

Chemical structure

Dansyl chloride.jpg

Synonyms and Related Terms

5-dimethylamino-1-naphthalenesulfonyl chloride; 5-dimethylamononaphthyl-5-sulfonyl chloride


  • Contact causes irritation and possible burns.
  • Fisher Scientific: MSDS

Physical and Chemical Properties

  • Soluble in acetone, acetonitrile, methylene chloride. Insoluble in water.
  • Maximum absorption wavelength = 335 nm.
  • Maximum emission wavelength = 500 nm.
Composition C12H12ClNO2S
CAS 605-65-2
Melting Point 72-74 C
Molecular Weight mol. wt.= 269.6025

Resources and Citations

  • Richard S. Lewis, Hawley's Condensed Chemical Dictionary, Van Nostrand Reinhold, New York, 10th ed., 1993
  • The Merck Index, Martha Windholz (ed.), Merck Research Labs, Rahway NJ, 10th edition, 1983 Comment: entry 2877
  • Aldrich Chemical Catalog Comment: p. 433